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How is rifampin metabolized? Rifampicin is extensively eliminated by intestinal and hepatic metabolism. The drug and its metabolites are largely excreted in bile and eliminated in stools. Since rifampicin is a potent enzyme inducer of the cytochrome P450 oxidase system, its administration is associated with numerous drug interactions.
Is rifampin a fluoroquinolone? Favourable responses with fluoroquinolones in regimens used in the treatment of clinical TB disease have been seen. They, however, are not to be considered as equal replacements for isoniazid or rifampicin (rifampin) and should be used with at least 2 other antituberculous agents.
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