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The more confusing healthcare becomes, and with the advance of health care reform, advocates will become more necessary, and more appreciated.

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Users may be apprised of the above information according to the invention.

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The present invention includes a method for applying multiple topical agents to a subject with pain comprising topically administering a pharmaceutical composition comprising a therapeutically effective amount of a topical diclofenac in DMSO, waiting for the treated area to dry (the time of which can be dependent on individual skin characteristics, environmental conditions such as temperature and humidity, and surface area, often about 5-30 minutes, about 5-20 minutes, for example, and typically about 10 minutes or less for a topical diclofenac preparation, including a topical diclofenac solution as described in the Examples), and applying another topical agents.

Do not prescribe diclofenac sodium topical solution to patients with the aspirin triad.

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Radioactivity in images taken immediately after washing was treated as % diclofenac penetrated through the skin; and radioactivity at subsequent time points were treated as % retention of diclofenac.

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