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Can I skip a week of methotrexate? A pragmatic approach may be to advise that a missed dose may be taken if it is up to 12 hours late, but if more than 12 hours late, patients should not take it and take their next dose at the normal time (5). Methotrexate once-weekly: doses should normally be taken on the same day each week (11,12).
How do you know if methotrexate is working? It can take 3 to 6 weeks to start to feel your methotrexate work. It takes even longer -- 12 weeks -- to get the full effects. Your doctor will test your blood often to check on how well your treatment works and to make sure it's safe for organs such as your liver.
What is rheumatrex? Rheumatrex (methotrexate) is an antimetabolite drug that is used to treat some cancers, severe skin diseases such as severe psoriasis, and to treat forms of rheumatoid arthritis.
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