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Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy.

This work was supported in part by the Norwegian Cancer Society; the Research Council of Norway; the Dr Einar Martens Foundation; the Grieg Foundation; and the Frank Mohn Foundation.

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Figure 2 Results of Cox Proportional-Hazards Analyses of Disease-free Survival, Overall Survival, and Time to Distant Recurrence, with Tamoxifen Followed by Letrozole as Compared with Letrozole Monotherapy and with Letrozole Followed by Tamoxifen as Compared with Letrozole Monotherapy.

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NSABP B-42: a clinical trial to determine the efficacy of five years of letrozole compared with placebo in patients completing five years of hormonal therapy consisting of an aromatase inhibitor (AI) or tamoxifen followed by an AI in prolonging disease-free survival in postmenopausal women with hormone receptor-positive breast cancer.

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